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1.
Health sci. dis ; 19(1): 51-58, 2018. ilus
Article in French | AIM | ID: biblio-1262786

ABSTRACT

Introduction. En 2017, la région de Diffa a notifié une hausse des cas de syndrome ictérique à huit cas dont 6 (75%) décès. Suite à la confirmation, une équipe multidisciplinaire a investigué cette flambée épidémique. L'objectif était de caractériser la population à risque, d'identifier la source de l'infection et de mettre en place des mesures de contrôle et de prévention. Méthodes. Nous avons conduit une étude descriptive des cas d'HVE survenus dans la région de Diffa, du 23 avril au 4 juin 2017. Une recherche active des cas a été menée dans les villages et les camps des réfugiés et des déplacés internes. Nous avons effectué des entretiens avec les malades et une revue documentaire. Une liste linéaire a été établie. Des prélèvements ont été collectés. Epi Info 7.2 pour l'analyse. Résultats. 329 cas dont 26 (7,90%) décès ont été enregistrés. Le sexe féminin représentait 63,1%. L'âge médian était de 26 ans (2 à 75 ans). La tranche d'âge ≥15 ans représentait 85,41%. Les femmes enceintes ou allaitantes représentaient 38,16% de l'effectif. Les signes cliniques étaient une fièvre, des céphalées, ictère, d'asthénies, de myalgies, d'arthralgies. Les populations se ravitaillaient en eau de boisson au niveau des abreuvoirs destinés aux animaux. La défécation se faisait à l'air libre dans les camps de réfugiés et des déplacés. Conclusion. L'investigation de l'épidémie a permis de décrire les cas et mettre en place des mesures de contrôle et de prévention. Nous recommandons de sensibiliser les populations sur l'hygiène et assainissement


Subject(s)
Hepatitis E/etiology , Hepatitis E/mortality , Hepatitis E/prevention & control , Niger
2.
Weekly Epidemiological Monitor. 2008; 01 (21): 1
in English | IMEMR | ID: emr-131882

ABSTRACT

Between epidemiological week no: 9 and 20 of 2008 [week ending 22 May 2008], the Red sea state of Sudan reported 208 cases of Acute Jaundice Syndrome [AJS] including 16 deaths [CFR: 7.6%]. Five serum samples, collected from the suspected cases, have tested positive for Hepatitis E at the National Public Health Laboratory [NPHL] in Khartoum. Most of these reported cases are females [72%] and majority of the cases [86%] are in the 15-44 year age group. Amongst the female cases, pregnant women [90%] constituted the majority of cases. The case fatality rate amongst the pregnant women was reported to be 37.5%. A Task force has been established in the affected state with a senior official incharge from the Federal Ministry of Health of Sudan to coordinate the overall public health response to contain this outbreak. The WHO Country Office in Sudan has been actively supporting this task force in its response operations


Subject(s)
Humans , Male , Female , Adolescent , Adult , Disease Outbreaks , Hepatitis E/mortality , Hepatitis E/transmission
3.
Article in English | IMSEAR | ID: sea-63746

ABSTRACT

INTRODUCTION: Acute liver failure due to acute hepatitis E carries a high mortality. METHODS: Clinical and laboratory parameters of 42 pregnant women (median age 25.5 years) with acute liver failure due to acute hepatitis E were retrospectively analyzed. RESULTS: 22 women delivered, whereas pregnancy continued in 20 women. The maternal mortality in these two groups was similar (9/22 [41%] versus 14/20 [70%], p=0.056). However, in patients with grade I, II or III hepatic encephalopathy, delivery of fetus was associated with reduced mortality in those who delivered as against those who continued pregnancy (5/16 (31%) vs. 13/20 (65%), p=0.046). On multivariate analysis, higher grade of encephalopathy at admission was associated with risk of death (p=0.005). CONCLUSION: Mortality in pregnant women with acute liver failure with acute hepatitis E is high, especially in patients who present with higher grades of encephalopathy.


Subject(s)
Adolescent , Chi-Square Distribution , Female , Hepatitis E/mortality , Humans , India/epidemiology , Liver Failure, Acute/mortality , Maternal Mortality , Multivariate Analysis , Pregnancy , Pregnancy Complications, Infectious/mortality , Pregnancy Outcome , Retrospective Studies , Risk Factors
4.
J. pediatr. (Rio J.) ; 73(6): 367-76, nov.-dez. 1997. ilus, tab
Article in Portuguese | LILACS | ID: lil-211797

ABSTRACT

Objetivo: os autores apresentaram uma revisäo dos diferentes tipos de hepatite viral na infância. Säo discutidos, com ênfase especial, os aspectos clínicos-laboratoriais e evolutivos das formas mais freqüentes da doença. Métodos: Foram selecionados, através de Medline, os artigos mais significativos publicados nos últimos anos sobre hepatite viral na infância. As características epidemiológicas säo discutidas, sempre que possível, levando em conta dados brasileiros. Resultados: A presente revisäo analisa as hepatites causadas por agentes que têm em comum a origem viral e o hepatotropismo mas que determinam doenças com diferenças marcantes sobretudo quanto a evoluçäo e prognóstico. Em relaçäo ao vírus B, por exemplo o paciente pode apresentar desde um simples estado de portador até hepatite aguda, hepatite crônica, cirrose...


Subject(s)
Humans , Child, Preschool , Child , Adolescent , Adult , Flaviviridae , Hepatitis A , Hepatitis A/diagnosis , Hepatitis A/therapy , Hepatitis B , Hepatitis B/diagnosis , Hepatitis B/therapy , Hepatitis D , Hepatitis D/diagnosis , Hepatitis D/transmission , Hepatitis E , Hepatitis E/mortality , Hepatitis E/transmission , Hepatitis, Viral, Human , Hepatitis, Viral, Human/diagnosis , Hepatitis, Viral, Human/etiology , Hepatitis Antigens , Immunologic Tests , Vaccines
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